Symbol Name ID |
Syk
spleen tyrosine kinase MGI:99515 |
* | Aspects of the system are reported to show a normal phenotype. |
Darker colors indicate more annotations |
Mouse Phenotypes | immune system phenotype |
abnormal osteoclast differentiation |
increased B cell proliferation |
impaired neutrophil phagocytosis |
abnormal B cell differentiation |
decreased late pro-B cell number |
arrested B cell differentiation |
abnormal NK cell differentiation |
increased neutrophil cell number |
decreased B cell number |
absent pre-B cells |
abnormal T cell number |
abnormal B cell morphology |
abnormal neutrophil physiology |
impaired granulocyte bactericidal activity |
abnormal lymphatic vessel morphology |
abnormal lymphangiogenesis |
abnormal lymphatic vessel endothelium morphology |
abnormal lymphatic vessel endothelial cell morphology |
decreased lymphatic vessel endothelial cell number |
enlarged lymphatic vessel |
lymphatic vessel hyperplasia |
abnormal dendritic cell antigen presentation |
decreased tumor necrosis factor secretion |
increased tumor necrosis factor secretion |
decreased inflammatory response |
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Availability | Mouse Genotype | ||||||||||||||||||||||||||
Sykm1Btlr/Sykm1Btlr | |||||||||||||||||||||||||||
SykM2Btlr/SykM2Btlr | |||||||||||||||||||||||||||
Syktm1.1Tara/Syktm1.1Tara | |||||||||||||||||||||||||||
Syktm1Paw/Syktm1Paw | |||||||||||||||||||||||||||
Syktm1Tyb/Syktm1Tyb | |||||||||||||||||||||||||||
SykM2Btlr/Syk+ | |||||||||||||||||||||||||||
Syktm1.1Nns/Syktm1.1Nns Commd10Tg(Vav1-icre)A2Kio/Commd10+ (conditional) |
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Syktm1.1Nns/Syktm1.1Nns Tg(Tie1-cre)9Ref/0 Commd10Tg(Vav1-icre)A2Kio/Commd10+ (conditional) |
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Syktm1.1Nns/Syktm1.1Nns Lyz2tm1(cre)Ifo/Lyz2+ (conditional) |
* | ||||||||||||||||||||||||||
Syktm1.1Nns/Syktm1.1Nns Tg(CD2-icre)4Kio/0 (conditional) |
* | ||||||||||||||||||||||||||
Syktm1.1Nns/Syktm1.1Nns Tg(Pf4-icre)Q3Rsko/0 (conditional) |
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Syktm1.2Tara/Syktm1.2Tara Tg(Itgax-cre)1-1Reiz/0 (conditional) |
* | ||||||||||||||||||||||||||
Syktm1.2Tara/Syktm1.2Tara Tg(Cr2-cre)3Cgn/0 (conditional) |
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Syktm1Tyb/Syktm1.2Tara Lyz2tm1(cre)Ifo/Lyz2+ (conditional) |
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Syktm1Tyb/Syktm1.2Tara Tg(S100A8-cre,-EGFP)1Ilw/0 (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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